Continuous Renal Replacement Therapy (CRRT) is a complex form of hemodialysis performed at selected facilities to provide care for patients who have ESRD or AKI and are hemodynamically unstable. It is generally performed continuously for 24 hours thus providing a slower form of dialysis and slower removal of fluid and toxins. The equipment utilized is specialized for CRRT and is generally performed in the ICU. It may be closely monitored and managed by a combination of SMG and ICU nursing staff. This therapy also requires access to the vascular space and as such requires either a permanent access such as an Arteriovenous Fistula (AVF) or an Arteriovenous Graft (AVG) or a temporary access such as a central venous catheter.